While both SSRIs were found to be effective, Zoloft was found to have lower severity of side effects. Out of randomized patients, 9. In a study from the Journal of Affective Disorders, Zoloft and Prozac showed similar effectiveness in patients with depression and anxiety.
The results from the study showed no significant differences in improvement and treatment with either drug. Paxil, or paroxetine, was also included in this study and was found to be comparable. Because every individual is different, one drug may be more suitable than the other. Consult a healthcare professional to determine which SSRI will give you the best results. Sometimes, it is a matter of trial and error. Sign up for Prozac price alerts and find out when the price changes!
Zoloft is usually covered by many insurance plans. Since it is available as a generic, the prices will often be quite reasonable. Get the SingleCare prescription discount card.
Prozac is usually started at a dose of 20 mg in a day supply. Prozac is available as a generic and is covered by most insurance plans.
Since both drugs are in the same class of medications, they both have similar side effects. These side effects are often mild and resolve on their own within weeks after starting treatment.
Consult your doctor to discuss any side effects you may experience. The most common side effects associated with Zoloft are nausea, diarrhea, indigestion, and tremors. The most common side effects with Prozac include nausea, nervousness, dry mouth, and indigestion. Changes in weight such as weight gain or weight loss are also common.
Other side effects for SSRIs may include sexual dysfunction, decreased libido, or impotence. Insomnia and other problems with sleep can also occur. More severe adverse effects include serotonin syndrome, a rare set of symptoms that can arise especially if you are taking other medications that increase serotonin activity.
Both medications can interact with monoamine oxidase inhibitors MAOI and increase the risk of serotonin syndrome. Zoloft and Prozac should not be used with linezolid or intravenous methylene blue for the same reason. Other drugs that are processed by this enzyme can interact with Zoloft and Prozac. These drugs include antipsychotics, benzodiazepines, antiarrhythmics, and some antidepressant drugs. Zoloft and Prozac can interact with blood thinners such as aspirin and warfarin.
Taking these medications together can increase the risk of bleeding. Consult a doctor for possible drug interactions with SSRIs. Antidepressants can increase the risk of suicidal thoughts in young adults and children.
Suicidal thoughts and behaviors should be monitored in individuals whose symptoms are not improving. Zoloft and Prozac can lower the seizure threshold in some people who have a history of seizures. Therefore, these drugs should be monitored or avoided in those affected groups. Zoloft and Prozac can cause QT prolongation, an electrical disturbance in the heart muscle. If you have a history of arrhythmias or abnormal heart rhythm, you may be at an increased risk.
The doctor will determine which combinations are the most appropriate for each person while keeping in mind the possibility of drug interactions. Doctors may also adjust medication dosages and regimens for people who are combining medication therapy and psychotherapy.
Zoloft is more likely than Prozac to cause gastrointestinal tract side effects, such as nausea and diarrhea. Men taking Zoloft may also report more sexual dysfunction side effects, such as failure to ejaculate, than those using Prozac. However, people taking Prozac more often experience headaches , nervousness, and a lack of energy. When people are ready to come off their antidepressant medications, they should do so gradually.
Stopping Prozac, Zoloft, or any other antidepressant abruptly can cause discontinuation symptoms. Discontinuation symptoms may include:. Several short-term studies have shown that children, adolescents, and young adults under 24 years old have an increased risk of suicidal thoughts and behaviors when taking any antidepressants. Doctors will monitor people taking Prozac, Zoloft, or any other antidepressant for worsening of depressive symptoms, suicidal thoughts , and unusual behaviors.
People with glaucoma and a history of seizures should use Prozac, Zoloft, and other SSRIs with caution because the drugs can make these conditions worse.
Serotonin syndrome is a potentially life-threatening interaction that occurs as a result of combining drugs that increase serotonin in the body. Doctors have reported QT prolongation in people taking Prozac and Zoloft. QT prolongation is a potentially fatal heart rhythm dysfunction.
This heart condition is more common in people who take other drugs that can prolong the QT interval on an electrocardiograph. These include certain antipsychotics, antibiotics , and anti-arrhythmic medications.
Some people can experience abnormal bleeding when combining Prozac, Zoloft, and other SSRIs with drugs that can increase bleeding, such as:. The following table compares the lowest available prices of Prozac and Zoloft :.
People should not take Prozac and Zoloft together. These drugs are in the same drug class and have the same actions. Taking both drugs will not improve symptoms but can cause additional side effects. When people are not feeling the intended effects of either Prozac or Zoloft, the doctor may increase the dosage or alter the treatment regimen by adding another antidepressant or antipsychotic drug that has different actions on the brain.
In this article, I will cover the difference between Zoloft and Prozac, and which conditions each drug can be used to treat. Prozac and Zoloft are both prescription drugs approved for the treatment of depression, anxiety , and other mental health conditions. Both increase serotonin levels in your brain, helping you to improve your mood, sleep, appetite, and quality of life.
But they are not the same drug. In addition, doctors will sometimes prescribe it in combination with other medications to treat patients with bipolar disorder. Both Prozac and Zoloft are considered powerful mental health medications , comparably effective at treating depression and reducing anxiety for the patients who take them. A few clinical trials suggest that Zoloft may have less serious side effects than Prozac.
It also may be slightly better at treating severe depression. If you have questions about whether you should be taking Prozac, Zoloft, or another anti-depression medication, seek medical advice from a healthcare professional to learn if one may be right for you. Antidepressant medications like Prozac and Zoloft can offer patients relief from symptoms related to anxiety, but effectiveness can vary depending on the individual, dosage, and condition treated. Although SSRI medications like Prozac and Zoloft often have similar side effects, patient experiences on these drugs are not always the same.
Common side effects of Prozac include:. Both medications carry the rare but serious risk of increasing suicidal thoughts and behaviors in teenagers and young adults. If you or someone you know is at risk of harming themselves or others, call or go to the nearest emergency room immediately. One study suggests that many patients lose weight after they begin taking antidepressant medication.
Researchers suggest that those who gain weight do so because they eat more nutritiously after being medicated for depression. Taking both medications will not increase their efficacy or make them work more quickly; it will only put you at an increased risk for adverse effects. Symptoms of this syndrome include heart palpitations, confusion, vision changes glaucoma , and seizures.
You should be evaluated in the emergency room right away if they occur. If you are concerned about whether your antidepressant drug is working for you, talk to your doctor. They may recommend changing your dosage or medication to something that will work better for your case. If you are experiencing depression while pregnant or breastfeeding, talk to your doctor about whether or not taking an SSRI medication is right for you.
Women with untreated depression may not receive adequate nutrition or seek prenatal care, putting their babies at risk for long-term health consequences. On the other hand, women who take antidepressant medications while pregnant, particularly while in their third trimester, may increase the risk of their child having withdrawal symptoms after they are born. In very rare cases, children exposed to SSRIs while in utero can develop persistent pulmonary hypertension, a condition that affects the lungs.
A few studies have also linked the use of SSRI medications particularly one called paroxetine during pregnancy with the increased risk of cardiac conditions in infants. For example, some people take antidepressant medications for a few weeks or months; others may take them much longer.
Some patients report an improvement in their mood and outlook in as little as two weeks of regularly taking their SSRI medications. If you have taken Prozac and Zoloft for at least eight weeks and are experiencing no change or worsening symptoms, talk to your doctor about adjusting your dosage or medication entirely.
SSRI medications carry a risk of withdrawal symptoms, including sore throat, nausea, insomnia, and hallucinations. Do not stop taking your medicine without talking to your doctor about how to wean off the drugs safely. Both Prozac and Zoloft can react poorly with other prescription medications, over-the-counter drugs, and homeopathic remedies.
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